Pace of aging

DunedinPACE

A methylation-based estimate of the pace of aging.

AI-assisted editorial draft · Source check: 6 September 2026 · Independent reviewer: not yet assigned

Method evidence: B. Peer-reviewed validation. This is a provisional editorial assessment of the stated method, not an endorsement of a test provider.

What it measures

A pace estimate calibrated to biological change per calendar year; it is not an age in years.

Source 1: eLife / Belsky et al.

Required inputs

Blood DNA-methylation data produced with a compatible assay and preprocessing.

How it was developed

The model was trained using longitudinal changes in multiple physiological measures in the Dunedin cohort, rather than simply fitting older versus younger people.

Source 1: eLife / Belsky et al.

Outcome associations

The primary paper reports associations with functional decline, morbidity and mortality in additional datasets.

Source 1: eLife / Belsky et al.

Limitations

A pace estimate does not reveal an exact future trajectory. Assay reliability and the studied populations matter. The provisional grade does not endorse every commercial report using this method.

Can you calculate it yourself?

Requires a methylation assay and the published analysis procedure; not a questionnaire calculation.

Commercial use

TruDiagnostic lists DunedinPACE as a TruAge output. WHOOP’s similarly named pace output is a different measure.

Source 1: eLife / Belsky et al.Source 2: TruDiagnostic
Check the original

Sources & verification

  1. DunedinPACE, a DNA methylation biomarker of the pace of aging (2022)

    eLife / Belsky et al. · Accessed 2026-09-06

  2. TruAge test: product, price and collection

    TruDiagnostic · Accessed 2026-09-06